{"id":1267,"date":"2023-08-26T07:25:06","date_gmt":"2023-08-26T07:25:06","guid":{"rendered":"https:\/\/staging.breastaware.gr\/?page_id=1267"},"modified":"2025-08-10T10:59:46","modified_gmt":"2025-08-10T10:59:46","slug":"%cf%80%ce%b1%cf%81%ce%ac%ce%b3%ce%bf%ce%bd%cf%84%ce%b5%cf%82-%ce%ba%ce%b9%ce%bd%ce%b4%cf%8d%ce%bd%ce%bf%cf%85","status":"publish","type":"page","link":"https:\/\/staging.breastaware.gr\/en\/%ce%ba%ce%b1%cf%81%ce%ba%ce%af%ce%bd%ce%bf%cf%82-%ce%bc%ce%b1%cf%83%cf%84%ce%bf%cf%8d\/%cf%80%ce%b1%cf%81%ce%ac%ce%b3%ce%bf%ce%bd%cf%84%ce%b5%cf%82-%ce%ba%ce%b9%ce%bd%ce%b4%cf%8d%ce%bd%ce%bf%cf%85\/","title":{"rendered":"Risk Factors"},"content":{"rendered":"
\n
\n\t

Risk Factors for Breast Cancer<\/strong><\/p>\n

Breast cancer is the most common malignancy in women worldwide. Although the exact cause of its occurrence remains unclear, we know that some risk factors<\/strong> significantly increase the likelihood of disease.<\/p>\n

It is important to emphasize that the presence of these factors does not necessarily mean<\/strong> that a woman will develop cancer, but it helps identify those who may benefit from prevention, early diagnosis<\/strong> or personalized monitoring.<\/strong><\/p>\n

\"\"<\/p>\n

Detailed List of Documented Risk Factors:<\/p>\n

    \n
  1. Sex<\/strong><\/li>\n<\/ol>\n

    Breast cancer occurs predominantly in women \u2014 about 100 times more frequently<\/strong> than in men.<\/p>\n

      \n
    1. Age<\/strong><\/li>\n<\/ol>\n

      The risk increases with age. While a 20-year-old woman has a 0.06% chance of developing cancer in a decade, that chance rises to 3.84% at 70 years<\/strong>. After 75-80, the risk gradually decreases.<\/p>\n

        \n
      1. Breast Density<\/strong><\/li>\n<\/ol>\n

        Women with dense mass tissue<\/strong> (mammographically) have up to 5 times higher risk<\/strong> occurrence of malignancy compared to those with less dense tissue.<\/p>\n

          \n
        1. Ethnicity<\/strong><\/li>\n<\/ol>\n

          In the USA, the white women<\/strong> has the highest rates of breast cancer, although black women more often develop more aggressive types.<\/p>\n

            \n
          1. Hormonal Factors<\/strong><\/li>\n<\/ol>\n
              \n
            • Early menarche<\/strong> (before age 12) or late menopause<\/strong> (after 55) increase risk due to prolonged estrogen exposure.<\/li>\n<\/ul>\n
                \n
              • The Childlessness<\/strong> or first pregnancy after 30<\/strong> is associated with increased risk.<\/li>\n<\/ul>\n
                  \n
                • The breastfeeding<\/strong> reduces risk: for every 12 months of breastfeeding, relative risk decreases by about 4,3%.<\/strong><\/li>\n<\/ul>\n
                    \n
                  1. Benign Breast Lesions<\/strong><\/li>\n<\/ol>\n

                    Benign tumors with atypical cells<\/strong> on biopsy carry a higher risk of future malignancy.<\/p>\n

                      \n
                    1. Personal and Family History<\/strong><\/li>\n<\/ol>\n
                        \n
                      • Women who have already had the disease have annual risk ~1%<\/strong> for cancer in the other breast.<\/li>\n<\/ul>\n
                          \n
                        • If there is 1st degree relative<\/strong> (mother, sister, daughter) with a history, the risk is doubled<\/strong> or is tripled<\/strong> if there is more than one relative.<\/li>\n<\/ul>\n
                            \n
                          1. Genetic Mutations<\/strong><\/li>\n<\/ol>\n

                            Approximately 5-10%<\/strong> of breast cancer cases are linked to mutations in genes such as:<\/p>\n

                              \n
                            • BRCA1<\/strong> and BRCA2<\/strong> (40-70% lifetime risk)<\/li>\n<\/ul>\n
                                \n
                              • TP53, PTEN, ATM, CHEK2<\/strong><\/li>\n<\/ul>\n
                                  \n
                                1. Hormonal Medications<\/strong><\/li>\n<\/ol>\n
                                    \n
                                  • The hormone therapy<\/strong> in menopause, especially when it contains estrogen and progestin,<\/strong> increases the risk.<\/li>\n<\/ul>\n
                                      \n
                                    • The Long-term<\/strong> use of contraceptives<\/strong> has a milder but still significant effect, which diminishes 10 years after stopping them.<\/li>\n<\/ul>\n
                                        \n
                                      1. Radiation Exposure<\/strong><\/li>\n<\/ol>\n

                                        The Therapeutic radiation to the chest<\/strong> (e.g. for Hodgkin lymphoma) at a young age increases the risk, especially if the exposure occurred before age 30.<\/p>\n

                                          \n
                                        1. Lifestyle<\/strong><\/li>\n<\/ol>\n
                                            \n
                                          • Alcohol consumption:<\/strong> Every 10g\/day (1 drink) increases risk by 7-10%.<\/li>\n<\/ul>\n
                                              \n
                                            • Smoking and<\/strong> and night shift<\/strong> work are also associated with higher risk.<\/li>\n<\/ul>\n
                                                \n
                                              • On the contrary, proper diet, regular exercise<\/strong> and healthy weight<\/strong> reduce the likelihood of disease.<\/li>\n<\/ul>\n
                                                  \n
                                                1. Obesity and Height<\/strong><\/li>\n<\/ol>\n
                                                    \n
                                                  • The Postmenopausal obesity significantly<\/strong> raises risk due to estrogen production in adipose tissue.<\/li>\n<\/ul>\n
                                                      \n
                                                    • Interestingly, taller women<\/strong> have a slightly increased risk, though the reasons are not fully understood.<\/li>\n<\/ul>\n

                                                       <\/p>\n

                                                      Conclusion<\/strong><\/p>\n

                                                      The knowledge of risk factors for breast cancer<\/strong> is the first step towards prevention and early diagnosis. Although we cannot control all factors, the education<\/strong> and the specialized prevention strategies<\/strong> make a difference.<\/p>\n

                                                      At breastaware.gr, you will find reliable, scientifically grounded information and practical prevention guides, empowering you to care for yourself responsibly and consciously.<\/p>\n

                                                       <\/p>\n

                                                      Sources:<\/i><\/strong>:<\/strong> WHO, American Cancer Society, Breast Cancer Now, National Cancer Institute, Lancet Oncology, JAMA, NEJM, Nature Reviews Cancer.<\/i><\/p>\n<\/div>\n<\/div><\/div><\/div>

                                                      <\/div>
                                                      <\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

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